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  • Top 10 Best Drugstore Face Serums: Anti Aging Serums That Really Work In 2021
Drugstore facial serum anti aging
Last updated on March 19, 2021
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Anti-aging serums are all the hype right now.

Despite being in the skincare sphere for many years now, it is only recently that companies and brands have gone mainstream with serums.

A lot of this has to do with the fact that Korean skincare is taking the world by storm with their “7 step skincare” regimen that includes the application of oils or serums every night.

Although the name may suggest that these serums are for women in their later years, you can and should be investing in and incorporating serums into your regimen from as early as 30 years of age.

For many of us, our skin has seen years and years of damage. From UV and sun damage, to dehydration and early signs of aging like wrinkles, acne scars, and spots.

Anti-aging serums can aid all your concerns and with continued use, you will see a drastic change in your skin’s overall appearance.

There are however, different serums for different skin concerns. For those of you with dry skin, opt for a serum that is rich in Vitamin E. If you have picky, acne prone skin, anything with Vitamin C will help alleviate the acne and brighten your skin.

Finally, if you have dull, discolored skin, a serum rich in antioxidants will bring the natural glow back to your face.

Here’s a list of some of the industry’s best drugstore anti-aging serums. There’s something for everyone when it comes to anti-aging serums and it is one of those things that should be considered an important investment in your skincare regime.

1. LilyAna Naturals Vitamin C Serum

Lily Ana Naturals

LilyAna Naturals, with is eclectic and fun branding offers a high potency grade Vitamin C serum that visibly reduces the look of wrinkles, hyper pigmentation, dark circles, and scars.

This best drugstore anti-aging serum is formulated with plant based ingredients and is suitable for both men, and women to use on a daily basis.

It won’t clog your pores so it’s great if you’re acne prone or have sensitive skin. Vitamin C is a known to brighten and lighten the skin so you can be sure to see a major difference in the overall glow and texture of your skin with continued use.

2. Tree of Life Retinol Serum

Tree of Life Retinol serum

Retinol is a hot ingredient in the skincare industry and serums are no exception when it comes to bottling this magical elixir!

Retinol and hyaluronic acid are blended together in this serum to boost the production of new cells and treat visible signs of aging.

Formulated with vitamin E, jojoba oil, green tea and witch hazel, this product helps you get smoother, plumper, and more radiant looking skin.

One of the best parts about this brand is that it is 72% organic, 98% natural, paraben free, and cruelty free.

3. Boots No7 Protect and Perfect Advanced Intense Facial Serum

Boots No 7

Boots has made monumental waves in the skincare industry over the past decade or so.

Their No7 line boasts a range of moisturizers and creams as well as serums and oils to help combat numerous skin cancers at an affordable price.

It best anti-aging serum in particular helps repair and protect your skin from concern related to signs of aging and sun damage.

According to the brand, it’s formulated with Matrixyl 3000 plus, which is a peptide that is made with two types of proteins. Essentially, this peptide has incredible anti-aging properties so you can rest reassured that your skin will feel refreshed, and look younger.

4. Olay Regenerist Regenerating Serum

Olay Regenerist

Olay is a leader when it comes to anti-aging skincare.

Known to work on all skin types, Olay offers a fragrance free serum that hydrates, brightens, smoothens, and plumps skin back into shape.

Formulated with their special Amino-Peptide Complex II, this extremely lightweight formula effectively treats fine lines and wrinkles as well as sun spots and other signs of aging. 

Filled with Vitamin E and carob extract, Olay aids surface cell regeneration for the look of brighter skin.

5. Cosmedica Skincare Hyaluronic acid


This 100% pure hyaluronic acid serum is bottled to treat uneven skin tone, dryness, fine lines and wrinkles, and it also helps reduce the look of dark, under eye circles.

It’s also perfect for sensitive skin. Hyaluronic acid works binds water to cells and effectively increases the surface hydration of skin.

Hydration is one of the most important aspects of an anti-aging routine because fine lines are caused often, by a lack of water in the skin’s cells.

6. TruSkin Naturals Vitamin C-Plus Super Serum

TruSkin Naturals

TruSkin offers four of the most important ingredients in skin-care regimens all in one bottle.

Retinol, Vitamin C, Niacinamide, and Hyaluronic acid work together in this perfect blend to create a powerful serum that tackles signs of aging, dehydration, acne issues, and dullness.

TruSkin is plant based, filled with vitamin B3, rose hip oil, aloe vera, salicylic acid, and pink grapefruit essential oil. This is one of those serums that truly has everything you could need.

It is however, a concentrated and strong serum which means that it’s important to do a patch test on your wrist to assess how your skin reacts to the product before applying it to your face.

7. RoC Retinol Correxion Deep Wrinkle Facial Serum

RoC Wrinkle Serum

Retinol makes another appearance, this time with RoC. This deep wrinkle serum actively reduces wrinkles and fine lines and works to improve the overall radiance and natural glow to the skin.

In fact, the brand maintains that after a mere 8 weeks of continued use, crow’s feet marks by the eyes, deep wrinkles, and sun damage are all visibly reduced.

It’s perfect to use under makeup and leaves no streaky residue so it’s great to use if you’re trying to incorporate a daily as well as nightly anti-aging routine into your skincare.

8. Drunk Elephant T.L.C. Framboos Glycolic Night Serum

Drunk Elephant Glycolic night serum

Drunk Elephant is an expensive but world renowned skincare brand that has made massive waves in the industry over the past few years. Again, as it is quite pricey, think of it as an investment.

Created with 12% AHA/BHA that works overnight to refine the surface of the skin to reveal your natural glow. If you have dull, congested, discolored skin, this product can help rejuvenate your face with just a few uses.

A blend of acids such as glycolic, tartaric, citric, and salicylic acids are blended with raspberry extract to counteract the effects of aging. Not only does it help in the anti-aging realm, dryness and pore size are also drastically improved.

9. Kleem Organics Serum

Kleem organics Vitamic serum

Kleem Organics has created a product that drastically changes the appearance of your skin in just 3 months of use.

Packed with vitamin C, it works to even the skin tone and reduce signs of sun damage, pigmentation, dark spots, discolouration and wrinkles.

The blend of ingredients will tighten your pores and improve the general elasticity of your skin. Vitamin C is actually a known catalyst in lightening and brightening the skin naturally. This is a lightweight formula that absorbs quickly, and leaves no streaky residue on site.

10. Eve Hansen Anti aging Set

Eve Hansen Anti Aging

The beauty of this set is that you get three products for the price of what is normally just one.

Three of the most popular anti-aging ingredients in the form of hyaluronic acid, vitamin C, and retinol, are packaged together and sun-proof dropper bottles to bring you the best of all three worlds.

This is a great option if you want to change your routine up according to varying concerns. You can mix and match and isolate different skin problems with this perfect trio.

Our Choice

   These are some of the best drugstore face serums that can give you younger looking skin without costing much.

We pick LilyAna Naturals as the best anti aging serum in this list. Results can vary upon skin type so try out some other brand in case you are not happy with a particular brand.

Laura Jones

Laura Jones is our chief editor and driving force behind this blog. She also works as a beauty consultant specializing in research and development of innovative and new age beauty products.She believes that sharing knowledge is the best way to improve the quality of life.

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